Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Virus or component thereof
Patent
1995-06-06
2000-06-13
Smith, Lynette R. F.
Drug, bio-affecting and body treating compositions
Antigen, epitope, or other immunospecific immunoeffector
Virus or component thereof
4242341, 4242651, 4242771, A61K 3921, A61K 3902, A61K 39002, A61K 3900
Patent
active
060746505
ABSTRACT:
According to certain embodiments, the invention relates to an immunoconjugate produced by conjugating at least one membrane-anchoring compound with at least one partial sequence of a protein of a virus, a bacterium, a parasite or a tumor antigen. The immunoconjugate has the advantage that it can be stored for a very long time even without cooling. According to certain embodiments, the invention relates to an immunogenic composition for the specific induction of cytotoxic T-lymphocytes which comprises a conjugate from at least one membrane anchor compound and a protein, containing at least one killer T-cell epitope, of a virus, a bacterium, a parasite or a tumor antigen, or at least one partial sequence containing at least one killer T-cell epitope of a viral, bacterial or parasite protein or of a tumor antigen.
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Deres Karl
Jung Gunther
Rammensee Hans-Georg
Schild Hansjorg
Wiesmuller Karl-Heinz
Hoechst Aktiengesellschaft
Nelson Brett
Smith Lynette R. F.
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