Meloxicam for oral administration

Details Meloxicam for oral administration Meloxicam for oral administration

2005-03-22

2005-03-22

Raymond, Richard L. (Department: 1624)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Heterocyclic carbon compounds containing a hetero ring...

C544S049000

Reexamination Certificate

active

06869948

ABSTRACT:
The invention relates in its first aspect to a rapidly decomposing tablet for pain therapy containing meloxicam [4-hydroxy-2-methyl-N-(5-methyl-2-thiazolyl)-2H-1,2-benzothiazine-3-carboxamide-1,1-dioxide] in the form of a salt with an inorganic or organic base providing rapid absorption of the active substance, the process of its preparation by direct tabletting, and furthermore relates in a second aspect to the crystalline meloxicam meglumin salt mono- and dihydrate and the preparation thereof.

REFERENCES:
patent: 4233299 (1980-11-01), Trummlitz et al.
patent: 4748174 (1988-05-01), Veronesi
patent: 37 00 172 (1987-07-01), None
patent: 0 002 482 (1979-06-01), None
patent: WO 97 17978 (1997-05-01), None
patent: WO 99 09988 (1999-03-01), None
Luger et al; “Structure and physicochemical properties of meloxicam, a new NSAID”; European Journal of Pharmaceutical Sciences; Bd. 4, 1996, Seiten 175-187, XP002074736 *siehe Zusammenfassung; Seite 177, linke Spalte; und Seite 178 Tabelle 1*.

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