Chemistry: molecular biology and microbiology – Vector – per se
Reexamination Certificate
2007-05-22
2007-05-22
Ketter, James (Department: 1636)
Chemistry: molecular biology and microbiology
Vector, per se
C536S024100, C514S04400A
Reexamination Certificate
active
10228897
ABSTRACT:
The invention provides for an isolated nucleic acid encoding Mda-5 (melanoma differentiation associated gene-5) and an isolated Mda-5 polypeptide. The invention further provides a vector comprising the nucleic acid encoding Mda-5, as well as a host cell comprising the vector. The invention provides an antibody which specifically binds to an Mda-5 polypeptide. The invention further provides a method for determining whether a compound is an inducer of Mda-5 gene expression and assays to determine whether a compound modifies the enzymatic activity of the Mda-5 polypeptide.
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Fisher Paul B.
Gopalkrishnan Rahul V.
Kang Dong-Chul
Baker & Botts LLP
Ketter James
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