Melanoma associated peptide analogues and vaccines against...

Details Melanoma associated peptide analogues and vaccines against... Melanoma associated peptide analogues and vaccines against...

2008-12-18

2010-12-07

Rawlings, Stephen L (Department: 1643)

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Amino acid sequence disclosed in whole or in part; or...

C530S328000, C514S015800

Reexamination Certificate

active

07846450

ABSTRACT:
The present invention is concerned with cancer treatment and diagnosis, especially with melanoma associated peptide analogues with improved immunogenicity, epitopes thereof, vaccines against melanoma, tumor infiltrating T lymphocytes recognizing the antigen and diagnostics for the detection of melanoma and for the monitoring of vaccination. The peptides according to the invention can be exploited to elicit native epitope-reactive Cm. Usage of the peptides with improved immunogenicity may contribute to the development of CTL-epitope based vaccines in viral disease and cancer.

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