Melanoma antigen peptide analogues

Details Melanoma antigen peptide analogues Melanoma antigen peptide analogues

2006-06-16

2009-10-20

Tsang, Cecilia (Department: 1654)

Chemistry: natural resins or derivatives; peptides or proteins;

Peptides of 3 to 100 amino acid residues

11 to 14 amino acid residues in defined sequence

C530S326000, C514S002600, C426S001000

Reexamination Certificate

active

07605227

ABSTRACT:
Some embodiments relate to analogs of peptides corresponding to class I MHC-restricted T cell epitopes and methods for their generation. These analogs can contain amino acid substitutions at residues that directly interact with MHC molecules, and can confer improved, modified or useful immunologic properties. Additionally, classes of analogs, in which the various substitutions comprise the non-standard residues norleucine and/or norvaline, are disclosed.

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