Melanocyte-stimulating hormone inhibitor and external preparatio

Details Melanocyte-stimulating hormone inhibitor and external preparatio Melanocyte-stimulating hormone inhibitor and external preparatio

1990-03-22

1992-06-30

Lee, Lester L.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Peptide containing doai

514 17, 514 16, 530330, 530329, A61K 3702, C07K 500

Patent

active

051263270

ABSTRACT:
A melanocyte-stimulating hormone inhibitor has an amino acid sequence represented by the following formula [I], [II] or [III] in the molecule:

REFERENCES:
patent: 4866038 (1989-09-01), Hruby et al.
Hawgood et al., Proc. Natl. Acad. Sci., vol. 84, pp. 66-70, (1987).
Chin et al., Nature, vol. 308, Apr. 12, 1984, pp. 613-617.
Nucleotide sequence of 3-hydroxy-3-methylglutaryl CoA reductase.
Sawyer et al., J. Med. Chem., 25, 1982, pp. 1022-1027, Comparative Biological Activity of Highly Potent Active Site Analogue.
Wu et al., Nucleic Acid Research, 10(13), 1982, pp. 3831-3843.
Nucleotide Sequence of a Chromosomal Rearranged .lambda..sub.2 immunoglobal.
Cashmore et al., Proc. Natl. Acad. Sci U.S.A., 81, May 1984 pp. 2960-2964.
Structure and Expression of a Pea Nucleargene Encoding a Chlorophy II.
Kameyama et al., "Expression of melanocyte stimulating hormone receptors correlates with mamalian pigmentation, and can be modulated by interferons", pp. 35-44, vol. 137, No. 1, 1988.
Hadley et al., "Biomedical Applications of Synthetic Melanotropins", Pigment Cell Research, Supplement 1 (1988), pp. 69-78.

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