Melanocortin receptor antagonists and agonists

Details Melanocortin receptor antagonists and agonists Melanocortin receptor antagonists and agonists

1997-11-28

2000-04-25

Woodward, Michael P.

Chemistry: natural resins or derivatives; peptides or proteins;

Peptides of 3 to 100 amino acid residues

Cyclic peptides

530312, 930270, C07K 500

Patent

active

060545569

ABSTRACT:
Cyclic lactam peptides are disclosed which inhibit at various levels of antagonism the melanocortin 1 receptor (MC1R), melanocortin 3 receptor (MC3R), melanocortin 4 receptor (MC4R), and Melanocortin 4 receptor (MC5R).

REFERENCES:
patent: 5731408 (1998-03-01), Hadley et al.
Degrado, W., Advances in Protein Chemistry, vol. 39, pp. 51-124 (see page ), 1988.

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