Melanocortin-4 receptor binding compounds and methods of use...

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

Reexamination Certificate

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C514S402000, C548S311400, C548S354100

Reexamination Certificate

active

07375125

ABSTRACT:
Provided are MC4-R binding compounds of the formula XVII:wherein L2is a linker group, and P1, P2, P3, P4, Z1, Z2, Z3, Z4, Z5, t, s, and R are as described in the specification. Methods of using the compounds to treat MC4-R associated disorders, such as disorders associated with weight loss, are also provided.

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