Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Recombinant dna technique included in method of making a...
Reexamination Certificate
2006-10-03
2006-10-03
Spector, Lorraine (Department: 1646)
Chemistry: molecular biology and microbiology
Micro-organism, tissue cell culture or enzyme using process...
Recombinant dna technique included in method of making a...
C536S023500, C530S300000, C530S350000, C435S320100, C435S325000
Reexamination Certificate
active
07115393
ABSTRACT:
The present invention relates to all facets of novel polynucleotides for melanocortin-1 receptors, the polypeptides they encode, antibodies and specific binding partners thereto, and their applications to research, diagnosis, drug discovery, therapy, clinical medicine, forensic science and medicine, etc. The polynucleotides are useful in variety of ways, including, but not limited to, as molecular markers, as drug targets, and for detecting, diagnosing, staging, monitoring, prognosticating, preventing or treating, determining predisposition to, etc., diseases and conditions especially relating to melanocortin-1, such as melanoma, pigmentation disorders and conditions, inflammation, etc.
REFERENCES:
patent: 6693184 (2004-02-01), Howard et al.
patent: WO 200039147 (2000-07-01), None
Mundy et al., Evolution of a pigmentation gene, the melanocrotin-1 receptor, in primates, Am. J. Phys. Anthr. 121:67-80, 2003.
Sturm et al., Human pigmentation genes:identification, structure and consequences of polymorphic variation, Gene 277:49-62, 2001.
NCBI Online Mendelian Inheritance in Man (OMIM) database, MIM 155555, “Melanocortin 1 Receptor; MC1R”, created Nov. 3, 1992, last updated Oct. 5, 2005.
Valverde et al., Variants of the melanocyte-stimulating hormone receptor gene are associated with red hair and fair skin in humans, Nat. Genet. 11(3):328-330, Nov. 1995.
Jay Gilbert
Li Xuan
Shu Youmin
Yee Anthony C.
Kaufman Claire M.
Millen White Zelano & Branigan P.C.
OriGene Technologies, Inc.
Spector Lorraine
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