Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Reexamination Certificate
2008-01-29
2008-01-29
Richter, Johann (Department: 1624)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
C514S327000, C514S331000
Reexamination Certificate
active
10820344
ABSTRACT:
Disclosed are compounds of the formula:and the pharmaceutically acceptable salts thereof wherein Q, X, Y, Z, and R1R9, and R12-R19are defined herein.These compounds are selective modulators of MCH1receptors that are, therefore, useful in the treatment of a variety of metabolic, feeding, and sexual disorders. Methods of treatment of such disorders and well as packaged pharmaceutical compositions are also disclosed.
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Kowalski et al., Therapeutic Potentila of Melanin-Concentrating Hormone-1 Receptor antagonists for the the treatment of Obesity; Expert Opinion Investig. Drugs (2004) 13(9): pp. 1113-1122.
Bakthavatchalam Rajagopal
Hutchison Alan
Thurkauf Andrew
Fidel Seth A.
Kadlecek Ann T.
Neurogen Corporation
Richter Johann
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