Meiotic spindle imaging in oocytes and uses therefor in in...

Image analysis – Applications – Biomedical applications

Reexamination Certificate

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C382S308000, C382S321000, C356S368000, C356S039000

Reexamination Certificate

active

06879713

ABSTRACT:
The developmental potential of a mammalian oocyte for successful implantation is evaluated by producing a plurality of intensity images of the oocyte using polarized light optics, and calculating a retardance image with a sensitivity of 3 nm or less. The presence, location and morphological characteristics of a meiotic spindle in the oocyte can then be determined based on the spindle structure in the retardance image, and the developmental potential of the oocyte can be evaluated.

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