Meglumine complex fungicidal polyene macrolide antibiotic compos

Drug – bio-affecting and body treating compositions – Conjugate or complex of monoclonal or polyclonal antibody,... – Conjugated via claimed linking group – bond – chelating agent,...

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536 17, A61K 3170

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active

040027414

ABSTRACT:
Medicated compositions which contain as active ingredients meglumine complexes of fungicidal polyene macrolide antibiotics and treatment method utilizing these compositions is described. These compounds possess fungicidal and protistocidal activity and are useful in the treatment of candidoses and aspergilloses. Additionally, meglumine complexes of amphotericin B and mycoheptine can be used for treating most systemic mycoses by way of oral and inhalation administration as well as by instillation, and for treating leishmaniasis, schistosomiasis, lambliasis and trichomoniasis.

REFERENCES:
abstracts of Communications, Vth International Congress of Biochemistry, Moscow, Aug. 10-16, 1961, Pergman Press, London, p. 61.

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