Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Cyclopentanohydrophenanthrene ring system doai
Patent
1992-05-13
1994-08-16
Cintins, Marianne M.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Cyclopentanohydrophenanthrene ring system doai
A61K 3156
Patent
active
053387325
ABSTRACT:
The present invention relates to a novel oral pharmaceutical composition of micronized megestrol acetate at a concentration of 15 to 150 mg/mL comprising polysorbate at a concentration of 0.005% to 0.015% weight/volume and polyethylene glycol at a concentration of 5-30% weight/volume which composition forms a stable flocculated suspension in water. The invention further comprises the micronized megestrol acetate formulation described above with added preservatives, buffers, sweeteners and flavoring agents.
REFERENCES:
patent: 3356573 (1967-12-01), Kirk et al.
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patent: 4396615 (1983-08-01), Petrow et al.
patent: 4402695 (1983-09-01), Wong
patent: 4666885 (1987-05-01), Labrie
patent: 4760053 (1988-07-01), Labrie
patent: 4775661 (1988-10-01), Labrie
J. H. Von Roenn, et al., Annals of Internal Medicine, 109, 840-841 (1988).
Atzinger Anne E.
Bequette Robert J.
Davis Robert E.
Bristol--Myers Squibb Company
Cintins Marianne M.
Jordan Kimberly R.
Kaye Michelle A.
Savitsky Thomas R.
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