Megakaryocytic protein tyrosine kinase I

Details Megakaryocytic protein tyrosine kinase I Megakaryocytic protein tyrosine kinase I

2005-06-21

2005-06-21

Kunz, Gary (Department: 1647)

Chemistry: natural resins or derivatives; peptides or proteins;

Proteins, i.e., more than 100 amino acid residues

C424S185100, C424S192100

Reexamination Certificate

active

06908984

ABSTRACT:
The present invention relates to novel cytoplasmic tyrosine kinases isolated from megakaryocytes (megakaryocyte kinases or MKKs) which are involved in cellular signal transduction pathways and to the use of these novel proteins in the diagnosis and treatment of disease. The present invention further relates to specific megakaryocyte kinases, designated MKK1, MKK2, and MKK3, and their use as diagnostic and therapeutic agents.

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