Megakaryocyte production

Details Megakaryocyte production Megakaryocyte production

1995-12-13

1998-06-09

Sayala, Chhaya D.

Drug, bio-affecting and body treating compositions

Lymphokine

424 852, A61K 4505

Patent

active

057629200

ABSTRACT:
A method of increasing megakaryocyte production is disclosed. Such method comprises administering to a mammal a pharmaceutically effective amount of G-CSF and a pharmaceutically effective amount of IL-3 or GM-CSF, and optionally a pharmaceutically effective amount of IL-6. Another method comprises administering GM-CSF and IL-5. Also disclosed are compositions for use in increasing megakaryocyte production. A method of increasing blood platelet production is also disclosed. Such method comprises administering to a mammal a pharmaceutically effective amount of IL-6 and optionally a pharmaceutically effective amount of IL-3, G-CSF or GM-CSF. Also disclosed are compositions for use in increasing blood platelet production.

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