Chemistry: molecular biology and microbiology – Animal cell – per se ; composition thereof; process of... – Method of culturing cells in suspension
Reexamination Certificate
2005-07-19
2005-07-19
Gambel, Phillip (Department: 1644)
Chemistry: molecular biology and microbiology
Animal cell, per se ; composition thereof; process of...
Method of culturing cells in suspension
C435S002000, C435S375000, C435S377000, C435S383000, C435S384000, C435S385000, C435S404000, C435S405000, C530S351000, C424S085200
Reexamination Certificate
active
06919206
ABSTRACT:
Ligands for flt3 receptors capable of transducing self-renewal signals to regulate the growth, proliferation or differentiation of progenitor cells and stem cells are disclosed. The invention is directed to flt3-L as an isolated protein, the DNA encoding the flt3-L, host cells transfected with cDNAs encoding flt3-L, compositions comprising flt3-L, methods of improving gene transfer to a mammal using flt3-L, and methods of improving transplantations using flt3-L. Flt3 -L finds use in treating patients with anemia, AIDS and various cancers.
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Beckmann M. Patricia
Lyman Stewart D.
Gambel Phillip
Immunex Corporation
Klaniecki James E.
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