Medicinal and/or nutritional microcapsules for oral administrati

Details Medicinal and/or nutritional microcapsules for oral administrati Medicinal and/or nutritional microcapsules for oral administrati

1995-10-17

2000-02-08

Page, Thurman K.

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Particulate form

424468, 424490, 424478, 424492, 424456, A61K 914

Patent

active

060225629

ABSTRACT:
The present invention relates to microcapsules for the oral administration of medicinal and/or nutritional active principles (AP), which are smaller than or equal to 1000 .mu.m in size. These microcapsules consist of particles which are coated with a coating material consisting of a mixture of a film-forming polymer derivative, a hydrophobic plasticizer, a functional agent and a nitrogen-containing polymer. These microcapsules are also characterized by their ability to remain in the small intestine for a long time (at least 5 hours) and to allow, during the residence, release and absorption of the AP. The invention also relates to a process for the production of the said microcapsules.

REFERENCES:
patent: 4461759 (1984-07-01), Dunn
patent: 5028434 (1991-07-01), Barclay et al.
patent: 5286497 (1994-02-01), Hendrickson et al.

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