Drug – bio-affecting and body treating compositions – Effervescent or pressurized fluid containing – Organic pressurized fluid
Patent
1995-05-31
1997-10-07
Page, Thurman K.
Drug, bio-affecting and body treating compositions
Effervescent or pressurized fluid containing
Organic pressurized fluid
424 44, 424400, A61L 904
Patent
active
056744730
ABSTRACT:
A self-propelling aerosol formulation which may be free from CFC's which comprises a medicament, 1,1,1,2-tetrafluoroethane, a surface active agent and at least one compound having a higher polarity than 1,1,1,2-tetrafluoroethane.
REFERENCES:
patent: 2868691 (1959-01-01), Porush et al.
patent: 2885427 (1959-05-01), Ruh et al.
patent: 3014844 (1961-12-01), Thiel et al.
patent: 3219533 (1965-11-01), Mullins
patent: 3261748 (1966-07-01), Larsen
patent: 3608066 (1971-09-01), Illartein
patent: 3897779 (1975-08-01), Hansen
patent: 4083954 (1978-04-01), Tsuchiya et al.
patent: 4129603 (1978-12-01), Bell
patent: 4161516 (1979-07-01), Bell
patent: 4174295 (1979-11-01), Bargigia et al.
patent: 4243548 (1981-01-01), Heeb et al.
patent: 4311863 (1982-01-01), Gumprecht
patent: 4352789 (1982-10-01), Thiel
patent: 4405598 (1983-09-01), Brown
patent: 4428854 (1984-01-01), Enjo et al.
patent: 4590206 (1986-05-01), Forrester et al.
patent: 4601897 (1986-07-01), Saxton
patent: 4814161 (1989-03-01), Jinks et al.
patent: 4851211 (1989-07-01), Adjei et al.
patent: 4866051 (1989-09-01), Hunt et al.
patent: 4983312 (1991-01-01), Tamura et al.
patent: 5118494 (1992-06-01), Schultz et al.
patent: 5126123 (1992-06-01), Johnson
patent: 5182097 (1993-01-01), Byron
patent: 5190029 (1993-03-01), Byron et al.
patent: 5225183 (1993-07-01), Purewal et al.
patent: 5290539 (1994-03-01), Marecki
patent: 5370862 (1994-12-01), Klokkers-Bethke
patent: 5376359 (1994-12-01), Johnson
patent: 5439670 (1995-08-01), Purewal et al.
patent: 5453445 (1995-09-01), Henry
patent: 5492688 (1996-02-01), Byron et al.
patent: 5496537 (1996-03-01), Henry
K. Thoma, Pharma Technologie, Concept Heidelberg, 1984, Seiten 94-102 (with translation).
T. Nelson, Alternative Formulations to Reduce CFC Use in U.S. Exempted and Excluded Aerosol Products, Report No. EPA-600/2-89-061; Nov. 1989.
Physicians' Desk Reference, 40th Edition 1986, Medical Economics Company Inc. at Oradell, NJ.
"Comparison of Output Particle Size Distributions from Pressurised Aerosols Formulated as Solutions or Suspensions", R.N. Dalby and P.R. Byron, Pharmaceutical Res., vol. 5, No. 1 (1988) p. 36.
The Theory & Practice of Industrial Pharmacy, Leon Lachman et al., 3rd Ed., Lea & Febiger 1986, Chapter 20, pp. 597, 599 and 603.
Chemical and Engineering News, 24 Nov. 1986, p. 52.
Dupont Update, Mar. 1987.
Manufacturing Chemist, May 1988.
HFC 134a as a Substitute Refrigerant for CFC 12, H.O. Spauschus, Paper presented 18 to 21 Jul. 1988.
Handbook of Aerosol Technology, Second Edition (1979), pp. 30, 32, and 33.
Product Information "Les Substituts F 22-F 502, FC 142b, F 123-F 134a, FC 141b", Atochem, dated Oct. 1988.
Dictionnaire Vidal (1979), pp. 392 - Chibro-Plast-, 1926 - Spray 1000 - and 2239-2240--Ventoline Aerosol-doseur.
F. Dorvalut "L'Officine" (1978), pp. 547-548.
Copy of the product Dexa-Rhinospray sold by C.H. Boehringer Sohn.
U.S. Senate Hearing, May 12-14, 1987, pp. 487 and 347.
The Theory and Practice of Industrial Pharmacy, 2nd Edition, 1976, Lea & Fabiger, Philadelphia, pp. 270 and 276-280.
"CFC-Gasser I Medicinske Spray", Mar. 1989, Pedersen et al., pp. 753-755.
"CFC Propellant Substitution: International Perspectives", Pharmaceutical Technology International, 1989, Fischer et al., pp. 16-18.
Aerosol Age, Nov. 1989, pp. 6, 8, 12, 16-19 and 24-26.
Manufacturing Chemist, Nov. 1989, p. 8.
International Journal of Refrigeration, 1988, 11, 389 (Spauschus, Nov. 1988).
Manufacturing Chemist, Feb. 1988, p. 9.
Processing, Dec. 1988, p. 7.
"Fluorocarbons and Ozone", Apr. 1988.
Manufacturing Chemist, Sep. 1988, p. 9.
Manufacturing Chemist, Jun. 1988, p. 3.
Aerosol Age, Jul. 1988, pp. 28-31, 32-33 and 42-43.
New Scientist, 26 May 1988, pp. 56-60.
Western Union "Mailgram", DuPont, Mar. 24, 1988.
Aerosol Age, Aug. 1988, pp. 32-39.
Research Disclosure, vol. 162, 1977, p. 70 (#16265).
New Scientist, p. 22, Apr. 23, 1987.
American Journal of Hospital Pharmacy, vol. 47, Jun. 1990.
Journal of Aerosol Medicine, vol. 4, No. 3, pp. 181-187, 1991.
SCRIP No. 1926, p. 30, May 27, 1994.
Rompps Chemie-Lexikon, 8th Ed., p. 3898, 1987.
Handbook of Aerosol Technology, 2nd Ed., pp. 30-35, 166-167 and 232-233, 1979.
Eur. Respir. J. 1990.
Medical Device Technology 5, 21-25, 1991.
K. Thoma, Aerosol--Moglichkeiten und Probleme einer Darreichungsform, Werbe- und Vertriebsgesellschaft Deutscher Apotheker m.b.H., Frankfurt a.M., 1979, Seiten 153-161 (with translation).
K. Thoma, Pharma Technologie, Concept Heidelberg, 1984, Seiten 94-102 (translation to follow).
H-FCKW 123 und H-FKW 134a, Frigen-Information KT Aug. 1988 (with translation).
Greenleaf David J.
Purewal Tarlochan S.
Benston, Jr. William E.
Griswold Gary L.
Kirn Walter N.
Page Thurman K.
Riker Laboratories Inc.
LandOfFree
Medicinal aerosol formulations does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Medicinal aerosol formulations, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Medicinal aerosol formulations will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-2354379