Organic compounds -- part of the class 532-570 series – Organic compounds – Nitrogen attached directly or indirectly to the purine ring...
Patent
1981-10-14
1985-01-15
Daus, Donald G.
Organic compounds -- part of the class 532-570 series
Organic compounds
Nitrogen attached directly or indirectly to the purine ring...
2602444, C07D40112, A61K 31495
Patent
active
044939302
ABSTRACT:
This invention relates to various 2-acetyl- and 2-propionylpyridine thiosemicarbazones which are substituted on the 4-nitrogen atom. These compounds are useful in the treatment of gonorrhea and, in addition, many are useful either in the treatment of malaria or bacterial infection. Also disclosed are several synthetic procedures used to prepare the thiosemicarbazones.
REFERENCES:
patent: 2719161 (1955-09-01), Behnisch et al.
patent: 2723270 (1955-11-01), Scudi
patent: 4317776 (1982-03-01), Klayman et al.
Collins, F. M., et al., J. General Microbiology, (1982), 128, 1349-1356.
Dobek et al., Antimicrobial Agents and Chemotherapy, vol. 18, (1), 27-36 80).
Bartosevich Joseph F.
Griffin T. Scott
Klayman Daniel L.
Mason Carl J.
Scovill John P.
Bellamy Werten F. W.
Daus Donald G.
Gapcynski William G.
Gibson S. A.
The United States of America as represented by the Secretary of
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