Medicaments for the treatment of hypertension

Details Medicaments for the treatment of hypertension Medicaments for the treatment of hypertension

1999-05-04

2000-06-06

Henley, III, Raymond

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

514397, A61K 3144, A61K 31415

Patent

active

060719397

ABSTRACT:
A composition comprising diethyl (E)-4-[2-[(tert-butyloxycarbonyl)vinyl]phenyl-1,4-dihydro-2,6-dimethylpyri dine-3,5-dicarboxylate (lacidipine) and 4'-[[2-n-propyl-4-methyl-6 -(1-methylbenziimidazol-2-yl)-benzimidazol-1-yl]-methyl]-biphenyl-2 -carboxylic acid (telmisartan) or a physiologically functional derivative thereof.

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Y. Fijimura et al., Japanese Pharmacology and Therapeutics 23(12): 887-93 (1995) (abstract).
P. Prasad et al., American Journal of Hypertension 10(4): 2 (Apr. 1997).
D. Neefe et al., American Journal of Hypertension 10(4): 2 (Apr. 1997).
G. MacGreggor et al., American Journal of Hypertension 10(4): 2 (Apr. 1997).
Dd. Wirth, Journal of Pharmaceutical Sciences 87(1):31 (Jan. 1998).
International Search Report for PCT/GB98/03336, dated Jul. 12, 1998.

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