Medicaments

Details Medicaments Medicaments

1989-08-15

1991-01-01

Goldberg, Jerome D.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Ketone doai

A61K 3112

Patent

active

049818740

ABSTRACT:
A method and certain compositions for treating Pneumocystis carinii infections in a mammal by administering a certain naphthoquinone compound or physiologically acceptable salts thereof.

REFERENCES:
patent: 2553648 (1951-05-01), Fieser et al.
patent: 3347742 (1967-10-01), Rogers
patent: 3367830 (1968-02-01), Sarett
Wofsy, Antimicrobial Therapy of Infections in Patients with Acquired Immunodeficiency Syndrome, pp. 377-401, Chapt. 36, 1986.
Fieser, et al., vol. 70, Oct. 1948, pp. 3156-3165, Naphthoquinone Antimalarials. II. Correlation of Structure and Activity Against P. lophurae in Ducks.sup.1.
Hughes, Parasitology Today, vol. 3, No. 11, 1987, pp. 332-335, Treatment and Prophylaxis for Pneumocystis carinii Pneumonia.
Parsons, 7.8.89, Central RD & Misbeckenham Chemical Information Group Enquiry Report, Novelty Search for Naphthalenes and Naphthoquinones.
M. Pudney, et al., Hydroxynaphthoquinones As Antimalarials, 11 pages, Oct. 1987.
Victoria S. Latter, Discovery and Development of New Antimalarial Hydroxynaphthoquinones, 28 pages, Oct. 1987.
A. T. Hudson, Topics in Medicinal Chemistry, Antimalarial Hydroxynaphthoquinones, No. 65, pp. 266-283.

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