Drug – bio-affecting and body treating compositions – Effervescent or pressurized fluid containing – Organic pressurized fluid
Patent
1990-11-29
1993-07-06
Goldberg, Jerome D.
Drug, bio-affecting and body treating compositions
Effervescent or pressurized fluid containing
Organic pressurized fluid
514682, A61K 904, A61K 3112
Patent
active
052251845
ABSTRACT:
The present invention relates to the treatment and prophylaxis of Pneumocystis carinii infections with 2-[4-(4-chlorophenyl)cyclohexyl-3-hydroxy-1,4-naphthoquinone.
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Group Research and Development, Document No. BTCB 87-18C, 28 pages, Oct., 1987.
Group Research and Development, Document No. BTCB 87-16C, 11 pages, Oct., 1987.
Constance B. Wofsy, Antimicrobial Agents Annual I, Antimicrobial therapy of infections in patients with acquired immunodeficiency syndrome, Chapter 36, pp. 377-400, (1986).
Topics in Medicinal Chemistry, Special Publication No. 65 (no date).
Central RD & Mis Beckenham, Chemical Information Group, Enquiry Report, Ref. BAQF/89-283, Issued Aug., 7, 1989, Novelty Search for Naphthalenes and Naphthoquinones.
W. T. Hughes, Parasitology, vol. 3, No. 11, 1987, Treatment and Prophylaxis for Pneumocystis carinii Pneumonia.
Fieser, et al., Naphthoquinone Antimalarials. II. Correlation of Structure and Activity Against P. lophurae in Ducks.sup.1, vol. 70, Oct., 1948, pp. 3156-3165.
Gutteridge Winston E.
Latter Victoria S.
Brown Donald
Burroughs Wellcome Co.
Goldberg Jerome D.
Green Hannah O.
Nielsen Lawrence A.
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