Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1990-05-15
1991-07-16
Friedman, Stanley J.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
A61K 3141
Patent
active
050326031
ABSTRACT:
The use of the compound of formula (II) or a physiologically acceptable salt or hydrate thereof in the treatment, relief or prevention of the effects of anxiety ##STR1## The compound of formula (II) is described in UK Published Patent Application No. 2157691A.
The preferred compound for use in this indication is (.+-.)-trans-5-fluoro-2,3,3a,9a-tetrahydro-1H-[1,4]-benzodioxino[2,3-c]-py rrole, especially in the form of its hydrochloride salt.
REFERENCES:
Life Sciences, vol. 33, pp. 19-29, Charney et al., Apr. 18, 1983.
Durcan et al., Psychopharmacology (1989), 97:189-193.
Halliday Clive A.
Oakley Nigel R.
Friedman Stanley J.
Glaxo Group Limited
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