Medicament formulation containing dihydropyridines and a process

Drug – bio-affecting and body treating compositions – Preparations characterized by special physical form – Liposomes

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264 41, 264 43, 264 46, 4284022, 424417, A61K 3722, A61K 2526, B32B 516, B01J 1302

Patent

active

049769642

ABSTRACT:
In the parenteral administration of a dihydropyridine, the improvement which comprises administering the dihydropyridine in an aqueous medium of pH 3 to 8.5 having dispersed therein liposomes with an average diameter of 20-1000 nm, the liposome membrane containng the following constituents by weight:

REFERENCES:
Chemical Abstracts, Band 91, 1979, Columbus, Ohio, USA, Y. Matsuno et al., "Lolubilizotion of nifedipine" Seite 350, Spalte 1, Zusammenfassung-Nr. 163 057s & Jpn. Kokai Tokkyo Koho, 79-55 714, Ota Pharmaceutical Co. Ltd.; Tokai Capsule Co., Ltd.
Chemical Abstracts 102: 2255k (1-7-85).

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