Drug – bio-affecting and body treating compositions – Preparations characterized by special physical form – Liposomes
Patent
1986-04-16
1990-12-11
Robinson, Douglas W.
Drug, bio-affecting and body treating compositions
Preparations characterized by special physical form
Liposomes
264 41, 264 43, 264 46, 4284022, 424417, A61K 3722, A61K 2526, B32B 516, B01J 1302
Patent
active
049769642
ABSTRACT:
In the parenteral administration of a dihydropyridine, the improvement which comprises administering the dihydropyridine in an aqueous medium of pH 3 to 8.5 having dispersed therein liposomes with an average diameter of 20-1000 nm, the liposome membrane containng the following constituents by weight:
REFERENCES:
Chemical Abstracts, Band 91, 1979, Columbus, Ohio, USA, Y. Matsuno et al., "Lolubilizotion of nifedipine" Seite 350, Spalte 1, Zusammenfassung-Nr. 163 057s & Jpn. Kokai Tokkyo Koho, 79-55 714, Ota Pharmaceutical Co. Ltd.; Tokai Capsule Co., Ltd.
Chemical Abstracts 102: 2255k (1-7-85).
Kazda Stanislav
Klinksiek Bernd
Schlossmann Klaus
Serno Peter
Zembrod Alfred
Bayer Aktiengesellschaft
Robinson Douglas W.
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