Medicament for treatment of neuropathies

Details Medicament for treatment of neuropathies Medicament for treatment of neuropathies

2000-07-27

2008-03-04

Kim, Jennifer (Department: 1617)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Heterocyclic carbon compounds containing a hetero ring...

C514S258100

Reexamination Certificate

active

07338955

ABSTRACT:
Compounds of formula (I) in which R1=C1-6alkyl, optionally halosubstituted; R2=H, C1-4alkyl, optionally halosubstituted or replaced by halogen; R3=C2-4alkyl, optionally halosubstituted; R4=SO2NR5R&, CO2R7or halogen, C2-4alkenyl; optionally substituted with NR5R6, SONR5R6, CONR5R6, CO2R7or halogen, C2-4alkanoyl, optionally substituted with NR5R6, SONR5R6, CONR5R6, CO2R7or halogen; R5and R6=independently H or C1-4alkyl, or, together with the N atom to which they are attached, a pyrrolidino, piperidino, morpholino, 4-(NR8)-1-piperazinyl or 1-imidazolyl ring optionally substituted with one or two C1-4alkyl groups; R7=H, C1-4alkyl, optionally fluorosubstituted, and R8=H,C1-3alkyl or hydroxyalkyl with 1-4 C atoms, or the pharmaceutically acceptable salts thereof are useful for the chemotherapeutic treatment of neuropathies.

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