Medicament for treating lung cancer

Details Medicament for treating lung cancer Medicament for treating lung cancer

2002-01-29

2010-02-09

McIntosh, III, Traviss C (Department: 1623)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Carbohydrate doai

C424S617000, C424S649000

Reexamination Certificate

active

07659257

ABSTRACT:
Lung cancer can be treated effectively by combination of amrubicin or a pharmaceutically acceptable salt thereof with cisplatin.

REFERENCES:
patent: 4673668 (1987-06-01), Ishizumi et al.
Sumitomo, “Amrubicin Hydrochloride”, Drugs of the Future, vol. 22, pp. 1271-1272, 1997.
Yanagi et al., abstract of the publication in Japanese Cancer Association, No. 2168, 1989.
Yamauchi et al., European Journal of Cancer, vol. 37:s 46, 159, 2001.
Takagi et al., “Effects of 13-hydroxy SM5887 in combination with other anticancer agents on human tumor lines”, Investigational New Drugs, 14:357-363, 1996.
Takigawa et al., “Comparison of antitumor activity of new anthracycline analogues, ME2303, KRN8602, and SM5887 using human lung cancer cell lines”, Acta Med Okayama (4) 249-246, 1992.
Yamaoka et al., “Cytotoxicity of amrubicin, a novel 9-aminoanthracycline, and its active metabolite amrubicinol on human tumor cells”, Jpn J Cancer res., 89, pp. 1067-1073, Oct. 1998.
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G. Colón-Otero et al., The Cancer Journal from Scientific American, vol. 3, No. 5 (Sep./Oct. 1997), pp. 297-302.
S. Yamauchi et al., Abstract of “Combination effects of amrubicin, a novel anthracycline, with cisplatin on human lung cancer cells”, European Journal of Cancer, vol. 37, Apr. 2001, pp. S46.
Sumitomo, Abstract of “Amrubicin Hydrochloride”, Drugs of the Future, vol. 22, No. 11, 1997, pp. 1271-1272.
T. Yamaoka et al., Jpn. J. Cancer Res., vol. 89, Oct. 1998, pp. 1067-1073.
D.S. Ettinger, Seminars in Oncology, vol. 28, No. 2, Suppl. 4 (Apr. 2001), pp. 27-29.
N. Takigawa et al., Acta Med Okayama, vol. 46, No. 4 (1992), pp. 249-256.
Tatsuya Takagi et al.,Investigational New Drugs, vol. 14, (1996), pp. 357-363.
Toyoaki Hida et al.,Clinical Cancer Research, vol. 6, (May 2000), pp. 2006-2011.
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The 48thAnnual meeting of the Japanese Cancer Association, (1989), No. 2168, (English Translation attached).

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