Medicament containing a tissue inhibitor of...

Details Medicament containing a tissue inhibitor of... Medicament containing a tissue inhibitor of...

2007-06-19

2007-06-19

Kam, Chih-Min (Department: 1656)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Peptide containing doai

C514S012200, C530S350000, C530S344000, C530S345000, C435S007100, C424S009100

Reexamination Certificate

active

10239870

ABSTRACT:
The invention relates to tissue inhibitor of metalloproteinase-2 (TIMP-2) as an osteoanabolically active peptide for use as a medicament for treating bone defects, bone diseases and for improving bone regeneration.

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patent: 5766585 (1998-06-01), Evans et al.
patent: 623676 (1994-11-01), None
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Voet et al., Biochemistry (John Wiley & Sons published), pp. 62-63 (1990).
Guo et al. , PNAS 101,9205-9210 (2004).
Yamashita et al., “Tyrosine phosphorylation is crucial for grown signaling by tissue inhibitors of metalloproteinases(TIMP-1 and TIMP-2)”,FEBS Letters, vol. 396, 103-107 (1996).

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