Medical uses of in situ formed gels

Drug – bio-affecting and body treating compositions – Preparations characterized by special physical form – Implant or insert

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424 7802, 424 7817, 424 7818, 424 7826, 424 7837, 424430, 424436, 424486, 424488, 424497, 5147727, 514779, 514912, 514913, 514914, 514944, 514966, 514967, 523122, A61K 3177, A61K 31725, A61K 3173, C08L 504

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053187806

ABSTRACT:
Balanced pH, hyperosmotic, hypoosmotic, or isoosmotic gels are ideal vehicles for drug delivery. They are especially suited for topical body cavity or injection application of drugs or diagnostic agents; for drug or diagnostic agent delivery to the eye of a mammal; as protective corneal shields; or as ablatable corneal masks useful in laser reprofiling of the cornea. The compositions without the addition of a drug or diagnostic agent are useful as medical devices, for instance, in separating surgically or otherwise injured tissue as a means of preventing adhesions.

REFERENCES:
patent: 4188373 (1980-02-01), Krezanoski
patent: 4570626 (1986-02-01), Norris et al.
patent: 4856513 (1989-08-01), Muller
patent: 4861760 (1989-08-01), Mazuel et al.
patent: 4911926 (1990-03-01), Henry et al.
patent: 4948575 (1990-08-01), Cole et al.
patent: 5071644 (1991-12-01), Viegas et al.
Cornea, In press, 1989, Reidy et al.

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