Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Radical -xh acid – or anhydride – acid halide or salt thereof...
Patent
1992-09-18
1994-11-01
Cintins, Marianne M.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Radical -xh acid, or anhydride, acid halide or salt thereof...
514872, 514561, 514213, 514214, 514221, 514568, 514569, 514648, 514649, 514650, 514654, 514322, 514317, A61K 3120, A61K 3155, A61K 31135, A61K 3119
Patent
active
053608208
ABSTRACT:
The present invention relates to the use of tachykinin antagonists, including substance P antagonists and other neurokinin antagonists, in the treatment of emesis. Also described are novel tachykinin antagonists of formula (I), processes for their preparation, pharmaceutical compositions containing them and their medical use. ##STR1## wherein R represents the ring A ##STR2## or 2-pyridinyl or 2-pyridinyl-N-oxide; R.sup.1 is selected from halogen atoms and C.sub.1-4 alkyl, C.sub.1-4 alkoxy, trifluoromethyl, and S(O).sub.n C.sub.1-4 alkyl groups;
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Bunce Keith T.
Coomber Barry A.
Hagan Russell M.
Ladlow Mark
McElroy Andrew B.
Cintins Marianne M.
Criares T. J.
Glaxo Group Limited
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