Surgery – Radioactive substance applied to body for therapy – Radioactive substance placed within body
Patent
1998-09-11
2000-12-12
Lacyk, John P.
Surgery
Radioactive substance applied to body for therapy
Radioactive substance placed within body
A61N 500
Patent
active
061591416
ABSTRACT:
A catheter apparatus (20) and radiation dosimetry unit indicator (21) for delivery of a prescribed radiation dose to a patient. The catheter is filled with a radiation carrier material such as an inert radioactive gas (12) for the treatment of, for example, restenosis after angioplasty, and malignancies. The inflated catheter includes a plurality of discrete chambers such as balloon sections (22, 24, 26) for transporting the radioactive carrier material, and a plurality of discrete chambers (32, 34, 36) enabling substantial blood flow through the artery during treatment with the prescribed radiation. The inflated catheter can also comprise a one-unit balloon. A specific metal coating enhances the radiation dose delivered to the target. The wall (25) of the inflation lumen attenuates transmission dose to the blood circulating through the hollow inner lumen of the catheter device. The system also creates increased by-product radiation, from the impact of beta particles and gamma protons traveling toward the lumen wall. A radiation dosimetry unit indicator (21) is positioned, disposed, or affixed to a calibrated catheter to assist the physician in prescribing radiation activity and exposure times.
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Popowski, Youri et al., Int. J. Radiation Oncology Biol. Phys., "Intra-arterial .sup.90 Y Brachytherapy: Preliminary Dosimetric Study Using A Specially Modified Angioplasty Balloon", vol. 33, No. 3., 1995, pp. 713-717.
Apple Marc G.
Bates Brian L.
DeFord John A.
Fearnot Neal E.
Cook Incorporated
Godlewski Richard J.
Lacyk John P.
Med Institute Inc.
Ness Anton P.
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