Prosthesis (i.e. – artificial body members) – parts thereof – or ai – Miscellaneous
Patent
1984-10-15
1987-11-03
Apley, Richard J.
Prosthesis (i.e., artificial body members), parts thereof, or ai
Miscellaneous
623 1, 623 2, 623 3, 623 11, 623 12, 427 2, 424 95, 128DIG8, A61F 204, A61F 206, A01N 102
Patent
active
047041315
ABSTRACT:
The medical material contains heparinized collagen in which heparin has been bonded to protamine covalently fixed on collagen, and, owing to its excellent compatibility with living bodies, especially, its superb antithrombotic property, can be suitably used as a substituent material for tissues or organs which are brought into direct contact with blood, namely, as aritificial vessels, artificial valves and patching materials for cardiovascular organs, and the above medical material is also suitable as a membrane having anti-adhesion effects. The medical material is obtained by immersing and treating a natural or artificial material successively in an aqueous protamine solution, an aqueous glutaraldehyde solution and an aqueous heparin solution.
REFERENCES:
patent: 3955012 (1976-05-01), Okamara
patent: 4175182 (1979-11-01), Schmer
patent: 4321711 (1982-03-01), Mano
patent: 4453939 (1984-06-01), Zimmerman
patent: 4510084 (1985-04-01), Eibl
Miyata Teruo
Noishiki Yasuharu
Apley Richard J.
Cannon Alan W.
Koken Co. Ltd.
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