Medical materials

Prosthesis (i.e. – artificial body members) – parts thereof – or ai – Miscellaneous

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623 1, 623 2, 623 3, 623 11, 623 12, 427 2, 424 95, 128DIG8, A61F 204, A61F 206, A01N 102

Patent

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047041315

ABSTRACT:
The medical material contains heparinized collagen in which heparin has been bonded to protamine covalently fixed on collagen, and, owing to its excellent compatibility with living bodies, especially, its superb antithrombotic property, can be suitably used as a substituent material for tissues or organs which are brought into direct contact with blood, namely, as aritificial vessels, artificial valves and patching materials for cardiovascular organs, and the above medical material is also suitable as a membrane having anti-adhesion effects. The medical material is obtained by immersing and treating a natural or artificial material successively in an aqueous protamine solution, an aqueous glutaraldehyde solution and an aqueous heparin solution.

REFERENCES:
patent: 3955012 (1976-05-01), Okamara
patent: 4175182 (1979-11-01), Schmer
patent: 4321711 (1982-03-01), Mano
patent: 4453939 (1984-06-01), Zimmerman
patent: 4510084 (1985-04-01), Eibl

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