Prosthesis (i.e. – artificial body members) – parts thereof – or ai – Arterial prosthesis – Stent structure
Patent
1988-04-25
1991-01-22
Cannon, Alan W.
Prosthesis (i.e., artificial body members), parts thereof, or ai
Arterial prosthesis
Stent structure
606151, A61F 206
Patent
active
049868314
ABSTRACT:
This invention is described and illustrated in connection with the generation of a homograft composed of collagenous tissue generated on a prosthetic device. A tubular substrate having generally cylindrical outside and inside surfaces is suspended in the lumen of a blood vessel of a living body. The tubular substrate is open at each end to permit blood to flow over both the inside and outside surfaces. One of the surfaces of the substrate is a thrombogenic surface or supports a thrombogenic mesh material to promote growth of a tube of collagenous tissue suitable for use as a surgical graft. The substrate is suspended in the blood flow of a blood vessel by an anchor which permits the substrate to freely move within the lumen of the vessel but is anchored by the tether to prevent the substrate from moving along the vessel in the direction of blood flow. The collagenous tissue growth about the substrate is generally tubular and suitable for use as a surgical graft.
The method of generating a homograft includes preparing a prosthesis composed of a tubular substrate. The substrate is open at each end to permit blood to flow along the length of the substrate inside wall. The substrate is selected to have at least one thrombogenic surface or a thrombogenic mesh material supported by the substrate. The prosthesis is inserted in the lumen of a blood vessel, either a vein or artery, of a living body and anchored in the lumen of the vessel to prevent the substrate from moving along the vessel with the blood flow. The body generates collagenous growth on the thrombogenic surface of the substrate while the substrate is freely suspended in the blood flow of the vessel. The substrate is then removed from the vessel after which a tubular homograft of collagenous tissue is removed from the substrate.
REFERENCES:
patent: 3688317 (1972-09-01), Kurtz
patent: 4190909 (1980-03-01), Ablaza
patent: 4743251 (1988-05-01), Barra
Gott et al.; "The Coating of Intravascular Plastic Prostheses with Colloidal Graphite", Surgery, vol. 50, #2, pp. 382-389, Aug., 1961.
Adams Theodore P.
Kane Lawrence M.
King Wendell L.
Angeion Corporation
Cannon Alan W.
Elwell Robert A.
Jastram Harold D.
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