Medical emulsion lubricant

Details Medical emulsion lubricant Medical emulsion lubricant

1997-09-23

2000-04-25

McAvoy, Ellen M.

Solid anti-friction devices, materials therefor, lubricant or se

Lubricants or separants for moving solid surfaces and...

Organic -co- compound

508427, 508428, 508513, 514937, 514938, C10M17300, A61K 9107

Patent

active

06054421&

ABSTRACT:
A medical lubricant suitable for injection into the blood stream of a patient. The lubricant is suitable for use with rotating equipment such as atherectomy drive shafts moving within sheaths and over guide wires. The lubricant is an oil-in-water emulsion including a surfactant and a co-surfactant. The lubricant can include a cryogenic agent and a pH buffer and be pH adjusted. One lubricant includes olive oil as an emulsified oil, egg yolk phospholipid as a surfactant, sodium deoxycholate as a co-surfactant, glycerin as a cryogenic agent, L-histidine as a pH buffer, and is pH adjusted using sodium hydroxide. The lubricant can withstand freeze/thaw cycles as well as saline dilution, heating, and shear stress without significant creaming, separation, or unacceptable increases in oil droplet size. Compared to saline, the lubricant provides significantly increased lubrication efficiency for rapidly moving parts.

REFERENCES:
patent: 52301 (1866-01-01), Lester
patent: 1525867 (1925-02-01), Koszyczarek
patent: 1857501 (1932-05-01), Gallagher
patent: 1934100 (1933-11-01), Stiepel
patent: 1970902 (1934-08-01), Brunstrum et al.
patent: 2192866 (1940-03-01), Musher
patent: 2210043 (1940-08-01), Scherr
patent: 2487377 (1949-11-01), Roehner et al.
patent: 3377276 (1968-04-01), Parker
patent: 4115313 (1978-09-01), Lyon et al.
patent: 4290910 (1981-09-01), Harada et al.
patent: 4337241 (1982-06-01), Ser et al.
patent: 4567045 (1986-01-01), Lyons
patent: 4695450 (1987-09-01), Bauer et al.
patent: 4703062 (1987-10-01), Blackburn et al.
patent: 4784845 (1988-11-01), Desai et al.
patent: 4816247 (1989-03-01), Desai et al.
patent: 4920098 (1990-04-01), Cotter et al.
patent: 4925677 (1990-05-01), Feijen
patent: 4985250 (1991-01-01), Bee et al.
patent: 4990134 (1991-02-01), Auth
patent: 5010067 (1991-04-01), Handley et al.
patent: 5041292 (1991-08-01), Feijen
patent: 5089268 (1992-02-01), Katz
patent: 5229023 (1993-07-01), Landis
patent: 5244925 (1993-09-01), Wretlind et al.
patent: 5256422 (1993-10-01), Albert et al.
patent: 5258184 (1993-11-01), Bee et al.
patent: 5266359 (1993-11-01), Spielvogel
patent: 5314407 (1994-05-01), Auth et al.
patent: 5331027 (1994-07-01), Whitbourne
patent: 5338471 (1994-08-01), Lal
patent: 5338761 (1994-08-01), Nakajima et al.
patent: 5364632 (1994-11-01), Benita et al.
patent: 5413725 (1995-05-01), Lal et al.
patent: 5427700 (1995-06-01), Stoffa
patent: 5427704 (1995-06-01), Lawate
patent: 5445812 (1995-08-01), Gotou
patent: 5461037 (1995-10-01), Cotter
patent: 5472706 (1995-12-01), Friedman et al.
patent: 5496479 (1996-03-01), Videau et al.
patent: 5595965 (1997-01-01), Wiggins
patent: 5616342 (1997-04-01), Lyons
patent: 5618779 (1997-04-01), Klein et al.
patent: 5626873 (1997-05-01), Weiner et al.
patent: 5645856 (1997-07-01), Lacy et al.
patent: 5656289 (1997-08-01), Cho et al.
patent: 5658864 (1997-08-01), Macpherson
patent: 5660858 (1997-08-01), Parikh et al.
patent: 5693337 (1997-12-01), Suzuki et al.
patent: 5703022 (1997-12-01), Floyd
patent: 5728678 (1998-03-01), Trimbo et al.
patent: 5736493 (1998-04-01), Garmier
patent: 5744153 (1998-04-01), Yewey et al.
patent: 5750142 (1998-05-01), Friedman et al.
patent: 5759563 (1998-06-01), Yewey et al.
patent: 5760020 (1998-06-01), Cotter
patent: 5801131 (1998-09-01), Coffey et al.
patent: 5843465 (1998-12-01), Lundquist
patent: 5858934 (1999-01-01), Wiggins et al.
patent: 5888947 (1999-03-01), Lambert et al.
Collins-Gold et al., "Parenteral Emulsions for Drug Delivery", Advanced Drug Delivery Reviews, vol. 5, May 1990, pp. 189-208.

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