Medical devices incorporating deuterated rapamycin for...

Details Medical devices incorporating deuterated rapamycin for... Medical devices incorporating deuterated rapamycin for...

2005-04-26

2005-04-26

Page, Thurman K. (Department: 1615)

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Implant or insert

C604S265000

Reexamination Certificate

active

06884429

ABSTRACT:
Deuterated rapamycin can be controllably introduced target locations within the patient's body by using an implantable medical device having a structure incorporated with a therapeutic agent comprising a deuterated rapamycin. Representative deuterated rapamycins include epi-7-deuteromthyl rapamycin, 7,43-d6rapamycin, 7-deuteromethyl rapamycin and 31,42-d2-rapamycin and isomers thereof, and mixtures thereof. The deuterated rapamycin can also be glycosylated.

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