Medical devices having antimicrobial coatings thereon

Drug – bio-affecting and body treating compositions – Preparations characterized by special physical form – Implant or insert

Reexamination Certificate

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Details

C424S400000, C514S772000

Reexamination Certificate

active

10287091

ABSTRACT:
The present invention provides a medical device, preferably a contact lens, which comprises an antimicrobial coating including at least one layer of polyquat of formula (I) or (II). The antimicrobial coating on the medical device of the invention has a high antimicrobial efficacy against microorganisms including Gram-positive and Gram-negative bacterial, a low toxicity, low coefficient of friction, and increased hydrophilicity while maintaining the desired bulk properties such as oxygen permeability and ion permeability of lens material. Such lenses are useful as extended-wear contact lenses. In addition, the invention provides a method for making a medical device, preferably a contact lens, having an antimicrobial coating thereon.

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Composition and Method for Inhibiting of Protein on Contact Lens (Assignee—Bausch & Lomb Incorporated), Dec. 14, 2001.
Bacterial Colonization of Functionalized Polyurethanes Flemming, Capelli, Cooper and Proctor, Elsevier Science Ltd.; 1999.

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