Drug – bio-affecting and body treating compositions – Preparations characterized by special physical form – Implant or insert
Reexamination Certificate
2008-07-22
2008-07-22
Hartley, Michael G. (Department: 1618)
Drug, bio-affecting and body treating compositions
Preparations characterized by special physical form
Implant or insert
C424S400000, C514S772000
Reexamination Certificate
active
10287091
ABSTRACT:
The present invention provides a medical device, preferably a contact lens, which comprises an antimicrobial coating including at least one layer of polyquat of formula (I) or (II). The antimicrobial coating on the medical device of the invention has a high antimicrobial efficacy against microorganisms including Gram-positive and Gram-negative bacterial, a low toxicity, low coefficient of friction, and increased hydrophilicity while maintaining the desired bulk properties such as oxygen permeability and ion permeability of lens material. Such lenses are useful as extended-wear contact lenses. In addition, the invention provides a method for making a medical device, preferably a contact lens, having an antimicrobial coating thereon.
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Ash Marcia Kay
Carney Fiona Patricia
Gabriel Manal M.
Lally John Martin
Morgan Courtney Flem
Hu Sheng-Hsin
Novartis AG
Silverman Eric E.
Zhou Jian
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