Medical devices having antifouling character

Details Medical devices having antifouling character Medical devices having antifouling character

2011-04-19

2011-04-19

Wax, Robert A (Department: 1615)

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Implant or insert

C428S473500, C528S170000, C528S219000, C528S271000, C528S322000, C528S363000, C528S392000, C528S425000

Reexamination Certificate

active

07927620

ABSTRACT:
According to an aspect of the invention, medical devices are provided which include (a) a substrate and (b) a coating that includes an antifouling copolymer, an adhesive copolymer, or both. Antifouling copolymers for use in conjunction with the present invention contain (i) at least one antifouling polymer block having multiple pendant alkoxy functional groups along the polymer backbone and (ii) at least one additional polymer block. Adhesive copolymers for use in conjunction with the present invention contain (i) at least one adhesive polymer block having multiple pendant ring-hydroxyl-substituted aromatic groups along the polymer backbone and (ii) at least one additional polymer block.

REFERENCES:
patent: 2003/0087338 (2003-05-01), Messersmith et al.
patent: 2005/0208093 (2005-09-01), Glauser et al.
patent: 2005/0245637 (2005-11-01), Hossainy et al.
patent: 2005/0266038 (2005-12-01), Glauser et al.
patent: 2006/0009550 (2006-01-01), Messersmith et al.
patent: 2008/0286333 (2008-11-01), Kangas
patent: WO 2006/055531 (2006-05-01), None
Statz et al. “New Peptidomimetic Polmers for Antifouling Surfaces” J. Am. Chem. Soc. 2005, 127, 7972-7973.
M. Zhang et al. “Proteins and cells on PEG immobilized silicon surfaces”,Biomaterials, 19, 1998, p. 953-960.
D.W. Branch et al., “Long-term stability of grafted polyethylene glycol surfaces for use with microstamped substrates in neuronal cell culture”,Biomaterials, 22, 2001, pp. 1035-1047.
Y. Zhang et al., “Study of protein absorption on polymer coatings surface by combining quartz crystal microbalance with electrochemical impedance methods”,Sensors and Actuators B, 108, 2005, pp. 933-942.
E. Ostuni et al., “A Survey of Structure-Property Relationships of Surfaces that Resist the Adsorption of Protein”,Langmuir, 2001, 17, pp. 5605-5620.
A.R. Statz et al., “New Peptidomimetic Polymers for Antifouling Surfaces”,J. Am. Chem. Soc., 2005, 127, pp. 7972-7973.
T. Horn et al., “Incorporation of Chemoselective Functionalities into Peptoids via Solid-Phase Submonomer Synthesis”,Bioconjug. Chem., 15, 2004, pp. 428-435.
J. Rennie et al., “Simple oligomers as antimicrobial peptide mimics”,J. Ind. Microbiol. Biotechnol, 2005, 32, pp. 296-300.
J. L. Dalsin et al., “Bioinspired antifouling polymers”,Materials Today, Sep. 2005, pp. 38-46.
Lee Ayres, “From structural proteins to synthetic polymers”, Doctoral Thesis, Radboud Universiteit Nijmegen, 2005, ISBN 9090198075, Chapter 1.
Lee Ayres et al., “Peptide-Polymer Vesicles Prepared by Atom Transfer Radical Polymerization”Journal of Polymer Science Part A: Polymer Chemistry, vol. 43, Issue 24, 2005, pp. 6355-6366.
Mattijs G.J. Ten Cate et al., “Sequence-Defined Polypeptide-Polymer Conjugates Utilizing Reversible Addition Fragmentation Transfer Radical Polymerization”,Macromolecules, 2005, vol. 38, No. 26, pp. 10643-10649.
Pyun et al., “Synthesis of Nanocomposite Organic/Inorganic Hybrid Materials Using Controlled/“Living” Radical Polymerization,”Chem. Mater., 13, 2001, pp. 3436-3448.
B. Reeves, “Recent Advances in Living Free Radical Polymerization,” Nov. 20, 2001, University of Florida, 14 pages.
T. Kowalewski et al., “Complex nanostructured materials from segmented copolymers prepared by ATRP,”Eur. Phys. J. E, 10, 2003, pp. 5-16.
N. V. Tsarevsky et al., “Step-Growth “Click” Coupling of Telechelic Polymers Prepared by Atom Transfer Radical Polymerization”,Macromolecules, 2005, 38, 3558.
Glenn Westwood et al., “Simplified Polymer Mimics of Cross-Linking Adhesive Proteins”, Macromolecules, 2007, 40, 3960-3964.

Affiliated with

Also associated with

Rating

Medical devices having antifouling character does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Medical devices having antifouling character, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Medical devices having antifouling character will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-2685296