Medical devices having an electrically conductive hydrogel coati

Details Medical devices having an electrically conductive hydrogel coati Medical devices having an electrically conductive hydrogel coati

1993-10-26

1995-04-04

Yasko, John D.

Surgery

Means for introducing or removing material from body for...

Treating material introduced into or removed from body...

A61M 3100

Patent

active

054032954

DESCRIPTION:

BRIEF SUMMARY
This invention concerns medical devices and more particularly such devices according to Patent Specification GB 2,219,510A.


BACKGROUND OF THE INVENTION

These last devices are for location at least partially within a patient's body for a period of at least the order of a day and comprise means operable to generate an electric field acting, in use of the device, to inhibit bacterial attachment and colonisation on and adjacent to the device/body interface. In one device form the generating means comprise an electrode for or in connection with an electrical circuit, the electrode being supported by the device and the circuit being operable to generate the appropriate field by way of the electrode.


DESCRIPTION OF THE INVENTION

According to the present invention the conductor in the last form of device comprises an electrically conductive hydrogel coating which itself serves to define the interface with the body during use of the device.
An advantage of the invention is that the subject devices may benefit in other ways from the application of a hydrogel coating. For example, catheters can be provided with such a coating to facilitate insertion in a patient by the reduction of frictional forces.
In order to ensure conductivity, with substantially predictable electrical properties, the hydrogel will be loaded with a salt, such as sodium or potassium chloride, or other appropriate material. Clearly this material should be compatible with both the patient's body and the hydrogel in the sense that it should give rise to no undesirable consequences.
Preferably, in addition, the hydrogel is loaded with material to regulate the pH level round the device. This pH buffer will stabilise the hydrogen ion concentration around the device when current is flowing in use.
The loading of material to ensure conductivity and provide a pH buffer can, of course, be effected in preparation of the hydrogel for application to the device during manufacture. However, insofar as the device may be made available to a user in a dehydrated form, which is to be rehydrated as a preliminary to use, loading can alternatively be effected by solution of the relevant material in the rehydration liquid. The invention accordingly also contemplates the provision of a device with a hydrogel coating in association with appropriate loading material and, correspondingly, the preparation of a device by the provision of a suitably loaded hydrogel coating.


BRIEF DESCRIPTION OF THE DRAWINGS

The invention is illustrated by way of example in the accompanying drawing which shows in schematic cross-section a device of tubular form, such as a catheter 10, having over its end portion for insertion in a patient a hydrogel coating 11.
As indicated above the coating is loaded with material to ensure conductivity and provide a pH buffer. Also, in order to ensure reliable connection with an associated electrical circuit, the catheter is provided with a terminal electrode 12 which is engaged by the coating and has a lead 13 connected therewith. The electrode 12 is suitably of annular form circumscribing the catheter towards its extracorporeal end, the electrode itself comprising a carbon-loaded zone of the plastics material from which the catheter is made or being of other suitable construction, and being at least partially superimposed by the coating in electrically conductive engagement.
1. A medical device for location partially within a patient's body for a period of at least the order of a day, said device comprising an electrode connectable with an electrical circuit operable to generate by way of said electrode an electric field acting in use of the device to inhibit bacterial attachment and colonization on and adjacent to the device/body interface, said electrode comprising a hydrogel coating to define said interface, said hydrogel coating being loaded with a salt to ensure conductivity with substantially predictable electrical properties, said hydrogel coating being dehydrated prior to use and requiring rehydration as a preliminary to use.
2. A device a

REFERENCES:
patent: 4569673 (1986-02-01), Tasi
patent: 4674512 (1987-06-01), Rolf
patent: 5205297 (1993-04-01), Montecallo et al.

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