Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...
Reexamination Certificate
2007-07-03
2007-07-03
Balasubramanian, Venkataraman (Department: 1624)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Heterocyclic carbon compounds containing a hetero ring...
C623S001110, C623S001200, C623S001420
Reexamination Certificate
active
10951120
ABSTRACT:
The present invention relates to methods and compositions comprising compounds that treat pathophysiological conditions arising from inflammatory responses. In particular, the present invention is directed to compounds that inhibit or block glycated protein produced induction of the signaling-associated inflammatory response in endothelial cells. The present invention relates to compounds that inhibit smooth muscle proliferation. In particular, the present invention is directed to compounds that inhibit smooth muscle cell proliferation by modulating HSPGs such as Perlecan. The present invention further relates to the use of compounds to treat vascular occlusive conditions characterized by smooth muscle proliferation such as restenosis and atherosclerosis.
REFERENCES:
patent: 3290305 (1966-12-01), Schmitz
patent: 3758471 (1973-09-01), Irikura et al.
patent: 3867383 (1975-02-01), Winter
patent: 4617390 (1986-10-01), Hoppe et al.
patent: 5062882 (1991-11-01), Newton et al.
patent: 5346691 (1994-09-01), Raspanti
patent: 5470921 (1995-11-01), Kaul et al.
patent: 5599576 (1997-02-01), Opolski
patent: 5651174 (1997-07-01), Schwartz et al.
patent: 5725568 (1998-03-01), Hastings
patent: 5759525 (1998-06-01), Raspanti et al.
patent: 5801224 (1998-09-01), Narayan et al.
patent: 5897696 (1999-04-01), Giodano et al.
patent: 5980551 (1999-11-01), Summers et al.
patent: 5981568 (1999-11-01), Kunz et al.
patent: 6117996 (2000-09-01), Lowe et al.
patent: 6123763 (2000-09-01), Kamikubo et al.
patent: 6150360 (2000-11-01), Daeyaert et al.
patent: 6153252 (2000-11-01), Hossainy et al.
patent: 6179817 (2001-01-01), Zhong
patent: 6187370 (2001-02-01), Dinh et al.
patent: 6218016 (2001-04-01), Tedeschi et al.
patent: 6239071 (2001-05-01), Giencke et al.
patent: 6249952 (2001-06-01), Ding
patent: 6273913 (2001-08-01), Wright et al.
patent: 6284710 (2001-09-01), Riebel et al.
patent: 6290729 (2001-09-01), Slepian et al.
patent: 6491617 (2002-12-01), Ogle et al.
patent: 2002/0051730 (2002-05-01), Bodnar et al.
patent: 2002/0065270 (2002-05-01), Moriarty et al.
patent: 19531084 (1997-02-01), None
patent: WO 00/47567 (2000-08-01), None
patent: WO-97/08156 (1997-03-01), None
patent: WO-99/31088 (1999-06-01), None
patent: WO 99/36410 (1999-07-01), None
patent: WO-01/40218 (2001-06-01), None
patent: WO 01/47897 (2001-07-01), None
patent: WO 01/47921 (2001-07-01), None
patent: WO-02/26139 (2002-04-01), None
patent: WO-02/26271 (2002-04-01), None
patent: WO 03/024926 (2003-03-01), None
Bennet, J. Ed., et al., Cecil Textbook of Medicine, 20th Ed., 1996, 1001-1010, W. B. Saunders Company.
Axford, J., “Glycosylation and Rheumatic Disease”, Biochimica et Biophysica Acta, 1999, 219-229, 1455, Elsevier Science B.V.
Stern, R., “Devising A Pathway For Hyaluronan Catabolism: Are We There Yet?”, Glycobiology, 2003, 105R-115R, vol. 13, No. 12, Oxford University Press.
Fattori, Rossella et al., “Drug-Eluting Stents in Vascular Intervention”, The Lancet, 2003, vol. 361, pp. 247-249.
Van Der Hoeven, Barend L. et al., “Drug-Eluting Stents: Results, Promises and Problems”, Int'l. Journal of Cardiology, 2005, vol. 99, pp. 9-17.
Indolfi, Ciro et al., “Molecular Mechanisms of In-Stent Restenosis and Approach to Therapy with Eluting Stents”, TCM, 2003, vol. 13(4), pp. 142-148.
Javed, Qamar et al., “Tumor Necrosis Factor-alpha Antibody Eluting Stents Reduce Vascular Smooth Muscle Cell Proliferation in Saphenous Vein Organ Culture”, Experimental and Molecular Pathology, 2002, vol. 73, pp. 104-111.
Alexander Christopher W.
Alluri Sesha Sridevi
Kumar Potlapally Rajender
Om Reddy Gaddam
Pal Manojit
Balasubramanian Venkataraman
Cepeda Milagros A.
Franks Robert A.
Reddy US Therapeutics Inc.
LandOfFree
Medical devices employing triazine compounds and... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Medical devices employing triazine compounds and..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Medical devices employing triazine compounds and... will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-3723337