Medical devices containing triggerable disintegration agents

Details Medical devices containing triggerable disintegration agents Medical devices containing triggerable disintegration agents

1994-09-27

1996-07-02

Michl, Paul R.

Surgery

Controlled release therapeutic device or system

Implanted dynamic device or system

424485, 424486, 424487, 424 48, 523113, 523115, A61K 922, A61K 914, A61F 200

Patent

active

055317359

ABSTRACT:
The invention discloses temporary medical devices such as stent implants which can be disintegrated in-vivo upon demand by release of an agent held trapped within the device. The device is fabricated from a matrix polymer material which is essentially insoluble in body fluids and a disintegration agent which acts to initiate decomposition of the matrix polymer when contacted therewith. The disintegration agent is trapped within and chemically isolated from the matrix polymer such as by encapsulation, and is releasable within the matrix polymer upon contact of the device with a releasing agent which liberates the encapsulated disintegration agent.

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patent: 4997443 (1991-03-01), Walthall
patent: 5084350 (1992-01-01), Chang
patent: 5160745 (1992-11-01), DeLuca et al.
patent: 5324519 (1994-06-01), Dunn et al.

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