Medical devices containing in-situ generated medical compounds

Coating processes – Medical or dental purpose product; parts; subcombinations;... – Particulate or unit-dosage-article base

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427 225, 427 23, 427343, 4274198, 623 1, 623 12, 606192, 606198, 604 8, 604 96, 604265, 600 29, 600 36, 424423, 424445, 424617, 424619, 424630, A61M 2500, B05D 118, B05D 724, B05D 136

Patent

active

058209182

ABSTRACT:
A process for impregnating a medical device made from a water absorbable polymer material, e.g., a hydrogel, with a medical compound having low solubility in aqueous solutions, e.g., an antiseptic or radiopaque compound, is disclosed. The device is first infiltrated with an aqueous solution containing a first water soluble, ionizable compound, and subsequently infiltrated with an aqueous solution containing a second water soluble, ionizable compound. The ionizable compounds are selected such that they react after mutual contact to form the medical compound in-situ within the device.

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