Medical devices comprising ionically and non-ionically crosslink

Details Medical devices comprising ionically and non-ionically crosslink Medical devices comprising ionically and non-ionically crosslink

1996-07-11

2000-05-09

Merriam, Andrew E. C.

Synthetic resins or natural rubbers -- part of the class 520 ser

Synthetic resins

Processes of preparing a desired or intentional composition...

523105, 524 28, 524916, 525903, 536 3, 424422, 424 7817, 623 1, 604264, A61K 922, C08K 324

Patent

active

060605340

ABSTRACT:
Shaped medical devices, e.g. stents, having improved mechanical properties and structural integrity are disclosed. The devices comprise shaped polymeric hydrogels which are both ionically and non-ionically crosslinked and which exhibit improved structural integrity after selective removal of the crosslinking ions. Process for making such devices are also disclosed wherein an ionically crosslinkable polymer is both ionically and non-ionically crosslinked to form a shaped medical device. When implanted in the body, selective in-vivo stripping of the crosslinking ions produces a softer, more flexible implant having improved structural integrity.

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