Medical device with sponge coating for controlled drug release

Details Medical device with sponge coating for controlled drug release Medical device with sponge coating for controlled drug release

2002-02-07

2008-12-09

Lucchesi, Nicholas D. (Department: 3763)

Surgery

Means for introducing or removing material from body for...

Treating material introduced into or removed from body...

Reexamination Certificate

active

07462165

ABSTRACT:
The medical devices of the invention comprise an expandable portion which is covered with a sponge coating for release of at least one biologically active material. The sponge coating is made of a non-hydrogel polymer having a plurality of voids. The device can further include means for infusing or expelling the biologically active material or drug into the voids. The drug is delivered to the body lumen of a patient by expelling the drug and inflating or expanding the expandable portion of the catheter or device.

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Mansoor Amiji and Kinam Park, “Surface Modification of Polymeric Biomaterials With Poly(Ethylene Oxide), Albumin, and Heparin for Reduced Thrombogenicity”, Purdue University, School of Pharmacy, West Lafayette, IN, 47907.

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