Medical device with biomolecule-coated surface graft matrix

Details Medical device with biomolecule-coated surface graft matrix Medical device with biomolecule-coated surface graft matrix

1997-03-07

1999-02-02

Webman, Edward J.

Drug, bio-affecting and body treating compositions

Solid synthetic organic polymer as designated organic active...

Aftertreated polymer

424 7818, 424486, 424487, 530815, 530816, 525 78, 427 224, 427 225, 427 228, 427 23, A61K 31765, A61K 3178, A61K 2700, C08L 3302

Patent

active

058661131

ABSTRACT:
A medical device having a surface graft matrix comprising carboxyl-functional groups located on the device, the surface graft matrix comprising an outer portion; and one or more biomolecules covalently coupled to the surface graft matrix, wherein a majority of the biomolecules are located in the outer portion of the surface graft matrix. The surface graft matrix can also be loaded with a pharmaceutical agent.

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