Drug – bio-affecting and body treating compositions – Preparations characterized by special physical form – Implant or insert
Patent
1995-06-07
1996-10-29
Azpuru, Carlos
Drug, bio-affecting and body treating compositions
Preparations characterized by special physical form
Implant or insert
424423, 424424, 424425, 424450, 427 212, 5147722, 514822, 523112, 523113, 604 53, 604266, 623 12, A61F 204, A01N 102, A61M 532
Patent
active
055694632
ABSTRACT:
A medical device and a method for its manufacture. The function of the medical device requires exposure of the device to the tissue of a patient. The device has a tissue-exposed portion constructed to release an agent that inhibits adverse reaction to the presence of the device defined by a polymeric surface-layer overlying in a supported manner a polymer defining a reservoir. The reservoir incorporates the agent in a manner that permits substantially free outward release of the agent from the reservoir and the overlying layer defines metering outward passages constructed to control the outward migration of the agent to enable prolonged release of the agent from the surface of the medical device to prevent the adverse reaction due to the presence of the device.
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Fish & Richardson P.C.
Helmus Michael N.
Raleigh Carol L.
Tolkoff M. Joshua
Azpuru Carlos
Harbor Medical Devices, Inc.
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