Chemistry: molecular biology and microbiology – Apparatus – Including measuring or testing
Reexamination Certificate
2007-11-06
2007-11-06
Le, Long V. (Department: 1641)
Chemistry: molecular biology and microbiology
Apparatus
Including measuring or testing
C604S065000, C604S066000, C604S067000, C604S267000, C604S272000, C604S191000, C435S006120, C435S007100, C435S287100, C424S422000, C424S449000, C422S068100
Reexamination Certificate
active
10937872
ABSTRACT:
The invention relates to an ingestible, implantable or wearable medical device comprising a microarray which comprises a bioactive agent capable of interacting with a disease marker biological analyte; a reservoir which comprises at least one therapeutic agent and is capable of releasing the therapeutic agent(s) from the medical device; and a plurality of microchips comprising a microarray scanning device capable of obtaining physical parameter data of an interaction between the disease marker biological analyte with the bioactive agent; a biometric recognition device capable of comparing the physical parameter data with an analyte interaction profile; optionally a therapeutic agent releasing device capable of controlling release of the therapeutic agent from the reservoirs; an interface device capable of facilitating communications between the microarray scanning device, biometric recognition device and the therapeutic agent releasing device; and an energy source to power the medical device. Specifically, the invention relates to a medical device capable of detecting an analyte in a bodily fluid comprising at least one microneedle capable of obtaining a sample of a bodily fluid, a first microchannel through which the sample flows and is in fluid communication with the at least one microneedle, a second microchannel in fluid communication with the first microchannel, through which a buffer flows, wherein the second channel comprises a microarray with a bioactive agent, a microarray scanning device to detect an interaction between the bioactive agent and the analyte in the bodily fluid; and an interface device.
REFERENCES:
patent: 4003379 (1977-01-01), Ellinwood
patent: 4146029 (1979-03-01), Ellinwood
patent: 4793825 (1988-12-01), Benjamin et al.
patent: 5279607 (1994-01-01), Schentag et al.
patent: 5716852 (1998-02-01), Yager et al.
patent: 5797898 (1998-08-01), Santini et al.
patent: 5801057 (1998-09-01), Smart et al.
patent: 5807375 (1998-09-01), Gross et al.
patent: 5820548 (1998-10-01), Sieben et al.
patent: 5832296 (1998-11-01), Wang et al.
patent: 5848991 (1998-12-01), Gross et al.
patent: 5874214 (1999-02-01), Nova et al.
patent: 5961923 (1999-10-01), Nova et al.
patent: 6123861 (2000-09-01), Santini et al.
patent: 6200814 (2001-03-01), Malmqvist et al.
patent: 6221677 (2001-04-01), Wu et al.
patent: 6245057 (2001-06-01), Sieben et al.
patent: 6319668 (2001-11-01), Nova et al.
patent: 6340588 (2002-01-01), Nova et al.
patent: 6352854 (2002-03-01), Nova et al.
patent: 6368275 (2002-04-01), Sliwa et al.
patent: 6372428 (2002-04-01), Nova et al.
patent: 6464687 (2002-10-01), Ishikawa et al.
patent: 6482593 (2002-11-01), Walt
patent: 6491666 (2002-12-01), Santini, Jr. et al.
patent: 6503231 (2003-01-01), Prausnitz et al.
patent: 6527762 (2003-03-01), Santini et al.
patent: 6542717 (2003-04-01), Zimmerman et al.
patent: 6544732 (2003-04-01), Chee et al.
patent: 6551838 (2003-04-01), Santini et al.
patent: 6632216 (2003-10-01), Houzego et al.
patent: 6649358 (2003-11-01), Parce et al.
patent: 6832296 (2004-12-01), Hooker
patent: 6929636 (2005-08-01), Von Alten
patent: 6966880 (2005-11-01), Boecker et al.
patent: 7112444 (2006-09-01), Beebe et al.
patent: 2001/0051766 (2001-12-01), Gazdzinshki
patent: 2002/0001854 (2002-01-01), Lee
patent: 2002/0034757 (2002-03-01), Cubicciotti
patent: 2002/0055127 (2002-05-01), Gindilis
patent: 2002/0072733 (2002-06-01), Flaherty
patent: 2003/0049833 (2003-03-01), Chen et al.
patent: 2003/0061687 (2003-04-01), Hansen et al.
patent: 2003/0069560 (2003-04-01), Adamis et al.
patent: 2003/0097092 (2003-05-01), Flaherty
patent: 2003/0117491 (2003-06-01), Avni et al.
patent: 2003/0143551 (2003-07-01), Cattell
patent: 2003/0148362 (2003-08-01), Luka
patent: 2003/0153900 (2003-08-01), Aceti et al.
patent: 2003/0167000 (2003-09-01), Mullick et al.
patent: 2003/0191430 (2003-10-01), D'Andrea et al.
patent: 2003/0214057 (2003-11-01), Huang
patent: 2004/0005582 (2004-01-01), Shipwash
patent: 2004/0096959 (2004-05-01), Stiene et al.
patent: 2005/0009101 (2005-01-01), Blackburn
patent: 2005/0019836 (2005-01-01), Vogel et al.
patent: 2005/0064529 (2005-03-01), Kwon
patent: 2005/0136548 (2005-06-01), McDevitt et al.
patent: 2005/0209565 (2005-09-01), Yuzhakov et al.
patent: 2006/0211933 (2006-09-01), Zimmermann et al.
patent: 2559986 (2003-07-01), None
patent: WO 94/01165 (1994-01-01), None
patent: WO 01/35928 (2001-05-01), None
Preininger et al. “Polymer-coated optical fibres for application in a direct evanescent wave immunoassay,” Analytica Chimica Acta. 403 (2000) 67-76.
Paul T. Charles, et al., “Synthesis of a Fluorescent Analog of Polychlorinated Biphenyls for Use in a Continuous Flow Immunosensor Assay,” Bioconjugate Chem, 1995, pp. 691-694, vol. 6, American Chemical Society.
Lorena Tedeschi, et al., “Antibody immobilization on fibre optic TIRF sensors,” Biosensors and Bioelectronics, 2003, pp. 85-93, vol. 19, No. 2, Elsevier B.V.
Warren C.W. Chan and Shuming Nie, “Quantum Dot Bioconjugates for Ultrasensitive Nonisotopic Detection,” Science, Sep. 25, 1998, pp. 2016-2018, vol. 281.
M. Celebre, et al., “A comparative study of efficiencies of fibre optic and prism TIRF sensors,” Measurement Science and Technology, 1992, pp. 1166-1173, vol. 3, IOP Publishing Ltd.
Marcel Bruchez Jr., et al., “Semiconductor Nanocrystals as Fluorescent Biological Labels,” Science, Sep. 25, 1998, pp. 2013-2016, vol. 281.
Kim E. Sapsford, et al., “Demonstration of Four Immunoassay Formats Using the Array Biosensor,” Analytical Chemistry, Mar. 1, 2002, pp. 1061-1068, vol. 74, No. 5, American Chemical Society.
Suresh K. Bhatia, et al., “Use of Thiol-Terminal Silanes and Heterobifunctional Crosslinkers for Immobilization of Antibodies on Silica Surfaces,” Analytical Biochemistry, 1989, pp. 408-413, vol. 178, Academic Press, Inc.
David C. Duffy, “Rapid Prototyping of Microfluidic Systems in Poly(dimethylsiloxane),” Analytical Chemistry, Dec. 1, 1998, pp. 4974-4984, vol. 70, No. 23, American Chemical Society.
Chang, et al. Micromachining & Microfabrication. SPIE Optical Engineering Press. Bellingham, Wash. 1997. (Cover pages and table of contents only).
Harrison's Principles of Internal Medicine, Part 2 Cardinal Manifestations of Disease, Ch. 60 (12th ed. 1991; pp. 338-343.).
Jaeger. Introduction to Microelectronic fabrication. Addison-Wesley Pubishing Co. Reading Mass. 1988. (Cover pages and table of Contents only).
Mukerjee, et al. Microneedle array for transdermal biological fluid extraction and in situ analysis. Sensors and Actuators A. 2004; 114:267-275.
Rai-Choudhury, ed., Handbook of Microlithography, Micromachining & Microfabrication, SPIE Optical Engineering Press. Bellingham, Wash. 1997. (Cover pages and table of contents only).
Runyan, et al. Semiconductor integrated circuit processing technology. Addison-Wesley Publishing Co., Reading Mass. 1990. (Cover pages and table of contents only).
Scheurle, et al. HER-2
eu expression in archival non-smaill cell lung carcinomas using FDA-approved hercep test. Anticancer Res. 2000; 20:2091-2096.
Holmes Elizabeth A.
Howard John
Roy Shaunak
Wang Chengwang
DiRamio Jacqueline A.
Le Long V.
Theranos, Inc.
Wilson Sonsini Goodrich & Rosati
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