Medical composition for injection containing a spergualin as act

Details Medical composition for injection containing a spergualin as act Medical composition for injection containing a spergualin as act

1987-08-11

1989-10-24

Phillips, Delbert R.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Peptide containing doai

514970, 514616, A61K 3702

Patent

active

048762440

ABSTRACT:
The present invention relates to a stable medical composition for injection containing (1) a Spergualin of the formula: ##STR1## [wherein R is ##STR2## (wherein R' is a lower alkyl group having 1 to 4 carbon atoms), ##STR3## or a salt thereof and (2) at least one stabilizer selected from the group consisting of mannitol, maltose, dextran, lactose, cyclodextrin, gelatin, chondroitin sulfate, and human serum albumin; when R is ##STR4## mannitol is excepted. A spergualin is useful as cancer control agents and immunomodulators.

REFERENCES:
patent: 4416899 (1983-11-01), Umezawa et al.
patent: 4430346 (1984-02-01), Umezawa et al.
patent: 4518532 (1985-05-01), Umezawa et al.
patent: 4525299 (1985-06-01), Umezawa et al.
patent: 4529549 (1985-07-01), Umezawa et al.
patent: 4556735 (1985-12-01), Umezawa et al.
Remington Pharmaceutical Science, 16th ed., Osol editor, Mack Publishing Co., pp. 252 and 1483, 1980.
The Merck Index, 9th ed., Martha Windholz editor, Merck and Co., Inc., Rahway, N.J., 1976, entry Nos. 2904, 2909, 4217, 8212 and 5575.

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