Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Phosphorus containing other than solely as part of an...
Patent
1985-09-20
1987-08-11
Friedman, Stanley J.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Phosphorus containing other than solely as part of an...
A61K 3166
Patent
active
046862110
ABSTRACT:
A medical composition for external application comprises a dialkyl phosphate represented by the formula: ##STR1## wherein R.sub.1 and R.sub.2 independently represent a hydrocarbon group having from 6 to 24 carbon atoms, R.sub.3 and R.sub.4 independently represent hydrocarbon group having from 2 to 6 carbon atoms, m and n independently represent a value of from 0 to 20, and x represents a hydrogen atom or a salt of an alkali metal and the like.
In the presence of the dialkyl phosphate, percutaneous intake of medically active ingredients is highly enhanced. Examples of the medically active ingredients directed to in the invention include antiinflammatory agents such as ethyl aminobenzoate; adrenocortical hormones such as hydrocortisone; etc.
The inventive composition is highly safe without giving any stimulation to the skin.
Hara Kenji
Kamiya Tetsuro
Takahashi Hiromichi
Tsujii Kaoru
Friedman Stanley J.
Kao Corporation
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