Prosthesis (i.e. – artificial body members) – parts thereof – or ai – Arterial prosthesis – Drug delivery
Reexamination Certificate
2004-03-19
2010-06-29
Stewart, Alvin J (Department: 3774)
Prosthesis (i.e., artificial body members), parts thereof, or ai
Arterial prosthesis
Drug delivery
C623S023720
Reexamination Certificate
active
07744644
ABSTRACT:
The medical articles which including the following: (a) a ceramic or metallic region whose surface includes a plurality of depressions, (b) a multilayer coating region including multiple polyelectrolyte layers deposited over the surface of the ceramic or metallic region; and (c) a therapeutic agent disposed beneath or within the multilayer coating region. According to another aspect of the present invention, medical articles are provided, which include: (a) a ceramic or metallic region, (b) a multilayer coating region including multiple polyelectrolyte layers deposited over a surface of the ceramic or metallic region, the multilayer coating region including a plurality of protuberances; and (c) a therapeutic agent disposed within regions beneath the protuberances. Also described herein are methods of making such medical articles, and methods of administering a therapeutic agent to a patent using such medical articles.
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Neuendorf Rachel
Weber Jan
Bonham David B.
Boston Scientific Scimed Inc.
Mayer & Williams PC
Park Keum J.
Stewart Alvin J
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