Medical article with adhered antimicrobial metal ions and relate

Prosthesis (i.e. – artificial body members) – parts thereof – or ai – Miscellaneous

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623 1, 623 11, A61F 254

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060131063

ABSTRACT:
Biocompatible articles for placement in a patient are described having releasably adhered antimicrobial metal ions. Furthermore, biocompatible articles made from biocompatible material for subcutaneous, percutaneous and cutaneous use are described where the biocompatible material has an attached exogenous storage structure with reversibly bound antimicrobial metal ions. The exogenous storage structures can include proteins such as ferritin, globulins, albumin, glutathione, transferrin, hemoglobin, metallothiens, myoglobin, ceruloplasmin and hemocyanin. Associated methods for imparting antimicrobial properties to biocompatible articles are described.

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