Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Reexamination Certificate
2005-11-03
2010-10-19
Saeed, Kamal A (Department: 1626)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
C514S321000, C546S118000, C546S271700, C546S273400
Reexamination Certificate
active
07816369
ABSTRACT:
The present invention makes available methods and reagents for inhibiting aberrant growth states resulting from hedgehog gain-of-function, ptc loss-of-function or smoothened gain-of-function comprising contacting the cell with a hedgehog antagonist, such as a small molecule, in a sufficient amount to aberrant growth state, e.g., to agonize a normal ptc pathway or antagonize smoothened or hedgehog activity.
REFERENCES:
patent: 6897208 (2005-05-01), Edwards et al.
patent: 2005/0085519 (2005-04-01), Rubin et al.
patent: 2006/0155771 (2006-07-01), Nordmark et al.
patent: WO 03/011219 (2003-02-01), None
patent: WO 03/008216 (2003-10-01), None
patent: WO 2005/002552 (2005-01-01), None
Boyd Edward Andrew
Boyd, legal representative Judith
Brunton Shirley Ann
Guicherit Oivin M.
MacKinnon Colin H.
Curis, Inc.
Genentech Inc.
Millen White Zelano & Branigan P.C.
Saeed Kamal A
Shterengarts Samantha L
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